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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5a1da31313f953866a1db19904cc5fe6a4e3868b5966553c0b01071a63822c6' 
  AND token = 'W0xQf0eO4A/l+ehnN2KpkaQFtpinzN3NnchmaE1m7yw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}