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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd745ed1d99821b121d6a6911d16e6c9b0b404e5afb374656957c19d28287a724' 
  AND token = 'ylWQABeJMPmal73GP8nOCeUeAz5uY3Pxuhsubu4rvuU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}