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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4eb08ae33490e62f8704ff924d236c379cb0832220ddf9872e095f655b0c80e2' 
  AND token = 'gt1vxcwA2ElBjcF3A6ADqa+tm0ZzrPbYOQOA2ScdaXE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}