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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc321be4ee0259f252a28d3c99190ba0afa18e0980953d916c40a2e7cbc56ed9' 
  AND token = 'tTEDiIhR1DDdtFpj/jz7VkK2jhkrv07pZHdKmt6SI9U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}