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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cdea7c26c3fdc3c7c2aa413b0028804ebd51f9747097deab7b8133bd46ee0b2' 
  AND token = '2kwXpwG8345W4jyoQ8NSBoqIH8m1a82VMxsVzMsEizs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}