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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f00827463e7352fcb7b8ccff8dacc5a9f549b5e3c4bb97541c293c346d546744' 
  AND token = 'Ff3OExqX7FIeoaEijMAzHNE9aOp7sb2O1pVCFrxtsHI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}