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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e4cc092a02b2f3f47ee4306441fe6285d7af107579c1e2d489674dd8c2a0d7c' 
  AND token = 'w3MPvxgNvbJBpIGfszPN06cpndW4H54S5DE4p8aSJaA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}