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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e45e15a133bbb39245d12e2974a0b1d4f9e608e0f921996379a94b3a1a817505' 
  AND token = 't4YD+iReH9qzbjUWMJ4Jym9RiHJ7kFM4CxIoKco851A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}