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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29e06930f1effd9dd4aafbe664079d2721db692609d1432fb45c9f93ca3451d0' 
  AND token = 'GG9r9dI/dprMar0Px/j6GMW5kh5Wd7Oor54ylaJiBkQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}