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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c11750759f7fa26d05e05a812aa93d2008235c845bceecfb972e9421075d2642' 
  AND token = 'D3uy8D7jm9r8TVLE8si4FAyP6tb+nJqC4PhncldQGW0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}