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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0880e6234f0a2cfcbad11c45ac5312316d0397e78481ccb7998134ffd5740aa3' 
  AND token = 'H8wYfvOcrlgWhVoWHbGQQH7aSZ02xu6Gpj056bk1EuQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}