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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f8b5900cb5325bab5922dae51b9b4d49b9fb67765f745b30e50d71bcc8b4df4' 
  AND token = 'JeysOEkLKEEJ/XGq7RyFHxK/OHaDZ2XjOzCQBqEZLyc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}