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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cb297ecdd92f40fc919293a131d9e3077b559023077673f336a6ac6eee3cdd2' 
  AND token = 'XNkpO03qR/4/kiXIMixJkXoZDSHsekH9yZGdR2g7Xbg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}