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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '370c55cd704d3df6f1b0b428c540cc06127f26d855c8269581046006a3bcfacf' 
  AND token = 'jKXBLcX7kawR8FnzDxYALPEy1V5E/fHKPYTb1n5csS0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}