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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a7e6823488517176857920a3aef44c1f2688ccaf5643d09c447e7076fa35875' 
  AND token = '+dfUuYNYtM+CpFB/IG23fdFEjg1Z3nO7EoVqPfC5rr4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}