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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c428b067a3ecc918005b063a5a46a3b338b0939599b2c57da734a545bc68b857' 
  AND token = '7ziYE+f5c0FHatXsYsGUriC1xd/NJ2p/cAgC/za2O0o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}