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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '882ac129eaa36046fff7dff4bbd4a2ac81380465f988df7d9a2ed9e89e5f2ade' 
  AND token = 'IETmHi3hco8FTF2dJ/hO9/lj9XFRLwcEn57roZ4RwLk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}