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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb2a8ef8d07caa8cf1453f946fa75fad1f55f6f78971117b44e36d7bc5bd406d' 
  AND token = 'NVM6LtL6CQFgIvGGteBxxl1J39fJFEJSNYeC9TcyAkg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}