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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e6ce08ee0d7346734e0b85150feae57120ae833e1bcd787063bf62377b7cefb' 
  AND token = 'l8v6q8odU0bnDNzMZWYObJ8xWU6GbgV7YWU3+hRmhOU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}