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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79209510433ef2e17a70a30e598d8b20e23306b8c7acc65f28f56d05e37a69d5' 
  AND token = 'JAgEG9n2jFdc1jxZxelGEAtNYTtnj5dVQDUS+KtMYsM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}