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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5a675b2f2046b71ac969d94749a8cd331662ebcf25d15882d1213c0660ee972' 
  AND token = 'zjmsr17iAy49ajRBMuIxGb65OvMElfJ9/E5VjnWo/sQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}