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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1ba7f5ed02e3273154aed346d886c4792a8f1db1a5635d1b2dd654aec3a6571' 
  AND token = 'f+kYiRDpeVZR/eiVzIpKSHfaXrC5975Tt38GTPAzcaY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}