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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2668164cc3c29b780f3d4715d8c9f6e51e919942fc6d08f0893217c71348f04a' 
  AND token = 'XD0Zp4evrj7PUaTTYa4o3ur5k4OtanSbZOjhM8LA+qI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}