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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef23b9ea5953733cd2bdd4c71f90a5665a6986faad29236e3aa72d04daadca4f' 
  AND token = 'KeVa0X68PNAGz3Yg4Y82y1dfqxsJ/kAiESK33Vgyog0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}