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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d5b82b5d967809ca79c3e60bcb9cc9750bd3f9a1718ed20a8fb00e739de710f' 
  AND token = 'p36udeq8Xa4TcrYTilbsbW9167YbIKlWTvpRtNniSX8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}