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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77bd602fd7b8baa0f2044149e9f75ad04aea07d256b67aab347865aaeefe26d5' 
  AND token = 'kCggTKZ5W9bKKgluWS9/rTq6TojME1ErG9xG5u6FyBo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}