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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46ba67dc05bf0d11beded69a6df2adaf894150d501f877aa4df454b7f3fba8f5' 
  AND token = 'KzIS+trjoFalvzgQF8A2s4ZDn5HWhscZmU2qWhpbovM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}