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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5517a1f607498a172913f446ebee8444548ef8660c40fc2561b687737d3d9c5' 
  AND token = 'e1K0vu/9uNj1eefL2buOZXywflCtW07+LjkYWLIuTEA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}