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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75b2b577e2b13251a5eb2e8632a9377a96b9aea368645ce23004e794bb98f66d' 
  AND token = 'T2XW/XvEZ95pLnY0fYeZNVj/D7bbV+MRb4LCNjw5rtU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}