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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b3bc908465c53a0f48c71e7871cade0635811057fb05a209b523a9b41fb6745' 
  AND token = 'P4ji1bRePJKLKNtJiCCcD+TkbPakml1oKjdFBxlRO6o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}