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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5149e6d0ebdff1cade0d247148fe23e27bf2ed1f477bb66e1bc985e36df1c01b' 
  AND token = 'T/F/JECQ+XG+35net3I7bvLObPkRoxJEQFfHVt+oNwM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}