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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '356cff6c392b0ced17f8b80d5a6d56d5f85c2221114bbf02c5e04c155208b236' 
  AND token = 'qw4JZjjok6zRSdN+PUMWLo8hy9SRcnloe4et1FVntjc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}