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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '992f4a7e35c74eeeb6425d5a7a324569ee2de9cbb4986099759271df1b8846f8' 
  AND token = '/mMs/6WllVjjikHpF3uKt74WCFNbcT/AUBp2jKdBbc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}