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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68e25505c2112f6571471b0ec8972f5d67e4ff2bbb6b84335051ac41c6ed961f' 
  AND token = 'D577eHZ4JoOPr8Qlg+yO9jwoTC5cLZBt/wB2j8oXnzo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}