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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d8b541b3799f80c00a870d5daf26b63d0d541f35c42a9e1d091fcfc9c62cd2b' 
  AND token = 'H02UfqiHCJkO1FuFHhphqOo/sRInVrV4BiGJ1CVPX50=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}