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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4007b0af4d34555b8fb847089f9f0b35e6e9ab1a84a03ef277d87b00e6a492cc' 
  AND token = 'ZFk/7UIQYebl+dw1wIAvdU0PRes/pE2+w3nmU0BkAOo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}