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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b099b2d8d8a2b30e6e5c14ca056437b376e85d905123b6f32faa0391f177f2b2' 
  AND token = 'FkxKNBEr62/VMPJ/+0SfDCMrINI5kSa2DLNJ5F9P5BQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}