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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea5f6e8d31997f8f1cf5277b85ce5f52350df7d7455d128831818a8047cec9fb' 
  AND token = 'dxpxYLOKaWIPb6ftqX5nfXD5M9+itJzGteBV/6oLO1c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}