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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9109c622dbd3e9ea3904622e03d56699ef386f248bf404ba16ca70471226c066' 
  AND token = 'Nol9yaQP4hCbTK+i7hcglqMlmrlobT7c1TgMndYuZnI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}