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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd360f78127037849781e040bb6522021e14c1987497fbb58cdcc70944c74b643' 
  AND token = 'PDA0HlOPcU+Ua0K2YGzOFOscwwkvkmEGluWeIoHdSLo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}