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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa1f8291ff8553048c2cd4985822c1b7842b9962f7a29feaec76ca69f6c48258' 
  AND token = 'K74Q/XA0Nc8Mb/pMVnmS7kEYlQuL7KIOATaEv1YMKzc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}