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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2c1faca05f446339eef10314cc5f2d65323592fa9b2e1f4fa4052cc9019fabd' 
  AND token = 's5tiakE99lURYJKGbCKbyvrTUS95UwbopQnt567YHyE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}