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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9443ad0ab116ea35ef481e39e9f99081bc25e3f1a8ace90b0cb16ad213c37415' 
  AND token = 't2/UOsLAmU+koAoS2q0CdkGD7tlhmlp9Znf9ClcYTSo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}