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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a784d317fa2267b81672a39e91552ed05a0a5ddbf623dbaeaa0a25b8dcb073b' 
  AND token = 'lwNjLsxUOW/pLt0wkvWKx5H/WEKyxFBu/5SLfVJXLiw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}