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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3d1b7e7cd6e936477a75415eca9747bec7ab261160a43646c9fe166b3cf946d' 
  AND token = 'AdxV7GCPv8WS+dH2Lgd9SBPZEWqqRBnpZS8s/TIVlIM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}