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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e1ff6efd98e85153e423e6321cc4f6b2909409a36890098b3d49b3b77b8bed3' 
  AND token = 'qa6b6y7wNDTxnQA6RQ2sZBhYeg68IvMIS8fWNfvQ4UY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}