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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72522366ed740df9ada017558d13c44ed1ba1254dd6387395530b20978d808b3' 
  AND token = 'ly/vykNILf90HWJQyMAmDmn2RRiSu3FjEVX8DydTVHE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}