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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ba8844f82cd8abebfd212aeaa7e6260ba9cd6f0b3a0707ead61c04e99fce112' 
  AND token = 'hPR1ko4LTiD68rcEXvRqf9h49sukuHO0YeZqWAqLLAc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}