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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c23d749327f1eb216a76488c633e47bc7a1166c030532bbdf2f0e0d456dce23' 
  AND token = 'fZ6lpZ9zcBzxH7zoQ9J0w7lXRHS/Sy5+12gE3sTB2gM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}