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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '484a53d7d590f5baf630cd0106d4a67382350d18af6a021a4c9edd9ed0cdec07' 
  AND token = 'c/rOp3+5/yIvY9vzP7hyBFt4Cr4BCjE5htStcc1hJDo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}